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Funding This work was supported in part by National Natural Science Foundation of China (No

The retrenchment occurred against a backdrop of a retreating large-cap pharma sector amid a positive broad market, but demonstrates the extreme sensitivity of investors to the longevity of Novo Nordisk's obesity dominance and pricing power

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This combination treatment alleviated multiple disorders in in vivo experiments, including cardiomyocyte hypertrophy, glucose and insulin tolerance, and Alzheimers disease, and is currently being tested in multiple clinical studies for different age-related diseases