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This suggests a duration-dependent relationship, though it has not been confirmed in prospective studies designed specifically to test this question
Chintan Dave explicitly emphasizes that because this is a registry-based observational study, it demonstrates a clear statistical association but does not prove direct cause-and-effect
This gives your GI system time to adapt to the slowed gastric emptying
Clinical studies show 20 to 30 percent improvement in skin firmness after 12 weeks, with significant gains occurring in this middle period
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