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Conceptual schematic illustrating the attenuation of circadian rhythm amplitude and phase shifts in aging, with a particular emphasis on nocturnal melatonin decline as a central driver of sleep fragmentation, metabolic dysregulation, and reduced antioxidant capacity ( The figure highlights age-related changes in key physiological variables, including restactivity cycles, core body temperature, hormonal secretion (melatonin and cortisol), suprachiasmatic nucleus (SCN) neuronal activity, and metabolic indicators such as glucose regulation
Abdel-Raheem IT, El-Sherbiny GA, Taye A
To learn more about the myelin sheath and its role in nerve health, read about how the nervous system works
Gadde KM, Allison DB, Ryan DH, Peterson CA, Troupin B, Schwiers ML
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