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Clinical data show that weight regain is common after GLP-1 medications are discontinued, including a STEP 1 trial extension where participants regained about two-thirds of prior weight loss one year after stopping semaglutide and lifestyle intervention
In practical terms, this means: Human-in-the-Loop: Every AI-generated piece of work that affects quality (SOP, specification, investigation report, etc.) must be examined and signed off by a qualified person in the QU ( [2] ) ( [13] )
doi:10.1002/oby.24067
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