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found that I/R was able to lead to liver damage, LPO as well as upregulation of the ferroptosis marker Ptgs2 in a murine model, and all of these effects were significantly alleviated by ferroptosis-specific inhibitor ferrostatin-1 and iron chelator deferoxamine [18]
Power is reduced by focusing on obesity class subgroups as compared to the main analysis, but the findings were consistent across obesity categories with no evidence for heterogeneity of treatment effects
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