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In addition to miRNA, long non-coding RNA XIST, as a competitive endogenous RNA of miR-29b, promotes HMGB1 expression, thereby enhancing ethanol-induced HSC autophagy and activation, thereby aggravating alcoholic liver fibrosis (Xie et al., 2019)
10.2337/diab.44.9.1126 21
GLP-1RA or dual GIP/GLP-1RA added to basal insulin compared to basal insulin titrated with a rigorous intention-to-treat approach is moderately effective in preventing further increase in daily basal insulin dose from achieving treat-to-target glycemic goals ( daily insulin dose, SMD -0.49, 95% CI -0.71
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