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Managing Side Effects: Guidance Based on Current Evidence Gradual dose escalation, dietary adjustments, and adequate hydration are the primary strategies for managing gastrointestinal side effects

Some clinicians also explore microdosing tirzepatide for inflammation benefits rather than purely for weight loss, which involves even lower doses with less GI impact

Analogs of GPP-1 and GIP burst onto the public scene, becoming incredibly popular among celebrities who wanted to lose weight

The weight loss supplement industry has seen dramatic shifts over the past year, driven largely by the popularity of GLP-1 receptor agonist medications