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The result is that you burn fewer calories at rest and you feel more tired

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At the 12 mg dose, mean HbA1c reductions from baseline reached approximately 2.2 percentage points (around 24 mmol/mol) at 24 weeks

Retatrutide Side Effects (Preliminary Data) Common (from Phase 2 data): Nausea (25-45% depending on dose) Diarrhea (20-35%) Vomiting (10-20%) Constipation (10-15%) Decreased appetite Notable differences: Mild increases in resting heart rate observed The glucagon receptor component may introduce metabolic effects not seen with GLP-1-only medications Full safety profile awaiting Phase 3 data The overall tolerability of retatrutide in the Phase 2 trial was described as acceptable, with most adverse events being mild to moderate