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Watermelon is considered a high FODMAP (fermentable oligosaccharides, disaccharides, monosaccharides, and polyols) fruit, which means it contains short-chain sugars that some people have trouble digesting, Derocha says, so it may cause bloating or discomfort when consumed in large amounts. People with diabetes or who may need to count their carbohydrate servings should also pay attention to their watermelon intake, she adds

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It has been studied in research settings for its role in pathways associated with growth hormone regulation