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They target receptors in the brain's appetite and reward centers
To exemplify, aripiprazole and risperidone have proven useful for controlling irritability, aggression and emotional dysregulation, compared to placebo (Salazar, et al., 2023)
Although the purpose of the study was not to conduct quantitative analyses, questionnaire data showed a trend towards reduction in PHQ-9, GAD-7 and EDE-Q scores (Table 1), which were clinically significant given that change scores of 5, 4 and 0.57 are considered the minimal clinically important differences in PHQ-9, GAD-7 and total EDE-Q scores respectively [38,39,40]
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